Treatment of constitutional growth delay in prepubertal boys with a prolonged course of low dose oxandrolone.
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چکیده
منابع مشابه
Treatment of constitutional growth delay in prepubertal boys with a prolonged course of low dose oxandrolone.
Forty six prepubertal boys who had constitutional growth delay were treated with oxandrolone. Mean age at the onset of treatment was 11.9 years (range 9.0-14.0) and bone age delay was 1.9 'years'. The dose of oxandrolone used was a mean of 0.05 mg/kg (range 0.03-0.18) for a mean of 0.9 years (range 0.2-3.6). Height velocity increased from a mean (SD) before treatment of 4.0 (1.0) to 7.5 (1.2) c...
متن کاملDouble blind placebo controlled trial of low dose oxandrolone in the treatment of boys with constitutional delay of growth and puberty.
Nineteen boys, mean age 14.4 years (range 12.9-16.3), with constitutional delay of growth and puberty were randomised into two groups in a double blind fashion for a three month period. Ten boys received oxandrolone, 2.5 mg per day (mean dose 0.072 mg/kg/day), and nine boys were treated with placebo. Mean growth velocity increased from 4.5 cm/year in the oxandrolone treated group to 9.6 cm/year...
متن کاملTreatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone.
The effects of oxandrolone or biosynthetic human growth hormone (r-hGH) on the growth of 26 boys with constitutional delay of growth and puberty were studied. Both regimens increased growth rate twofold, oxandrolone to a greater extent than r-hGH. We conclude that oxandrolone is a more effective method of increasing growth rate in such children.
متن کاملBone mineral status in prepubertal children with constitutional delay of growth and puberty.
OBJECTIVE We wished to clarify whether the osteopenia reported in adult men with a history of constitutional delay of growth and puberty (CDGP) could be due to the delayed puberty or an independent predisposition to osteoporosis in this condition. DESIGN Short prepubertal children with CDGP and children with familial short stature (FSS) were matched for height and other auxological variables....
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1991
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.66.7.841